Wireless sensor network is one of the most effective communication mechanisms in the present world. The current research is combating in crossing over the limiting boundaries. Despite the immense growth of wireless sensor communication, there are many challenges such as conflicts, middle-man attack, loss of energy, optimized path, etc. This special issue invites researchers to provide new directions in addressing the current challenges in identifying different routing algorithms with energy efficient protocols to make the most effective transfer of information. It will focus very specifically on bringing the current edge opinions on the artificial neural network- based wireless communication systems.