Technological advancement of infrared sensors is particularly important for biomedical research. This Special Issue aims to create a sharing opportunity between experts on infrared sensors development and scientists that apply such technology within the biomedical field through software, experimental procedures, or novel applications. Different innovative detectors, sensitive to different ranges of the infrared spectrum (from near- to far- infrared; e.g., Silicon Photomultipliers, Bolometers, Quantum Well Detectors, etc.), and application that relies on such sensors, with emphasis on, but not only, wireless or portable technologies, are suitable topics. Original papers that describe new research or innovative biomedical application are welcome. We look forward to, and welcome, your participation in this Special Issue.